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Med Phys. 2014 Jun;41(6):064301. doi: 10.1118/1.4871617.

A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications.

Author information

1
Université de Lyon, CREATIS; CNRS UMR5220; Inserm U1044; INSA-Lyon; Université Lyon 1; Centre Léon Bérard, France.
2
Inserm, UMR1037 CRCT, F-31000 Toulouse, France and Université Toulouse III-Paul Sabatier, UMR1037 CRCT, F-31000 Toulouse, France.
3
INSERM, UMR 1101, LaTIM, CHU Morvan, 29609 Brest, France.
4
Université de Lyon, CREATIS, CNRS UMR5220, Inserm U1044, INSA-Lyon, Université Lyon 1, Centre Léon Bérard, 69008 Lyon, France.
5
CEA/DSV/I2BM/SHFJ, Orsay 91401, France.
6
Department of Medical Instruments Technology, Technological Educational Institute of Athens, Athens 12210, Greece.
7
UMR 6533 CNRS/IN2P3, Université Blaise Pascal, 63171 Aubière, France.
8
Department of Biomedical Engineering, Technological Educational Institute of Athens, 12210, Athens, Greece.
9
Institut für Neurowissenschaften und Medizin, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany and Fachbereich für Mathematik und Naturwissenschaften, Bergische Universität Wuppertal, 42097 Wuppertal, Germany.
10
IMNC, UMR 8165 CNRS, Universités Paris 7 et Paris 11, Orsay 91406, France.
11
Delft University of Technology, Faculty of Applied Sciences, Radiation Science and Technology Department, Delft Mekelweg 15, 2629 JB Delft, The Netherlands.
12
INSERM U1101, LaTIM, CHU Morvan, 29609 Brest, France.
13
IMNC, UMR 8165 CNRS, Universités Paris 7 et Paris 11, 91406 Orsay, France and CEA/DSV/I2BM/SHFJ, 91400 Orsay, France.

Abstract

In this paper, the authors' review the applicability of the open-source GATE Monte Carlo simulation platform based on the GEANT4 toolkit for radiation therapy and dosimetry applications. The many applications of GATE for state-of-the-art radiotherapy simulations are described including external beam radiotherapy, brachytherapy, intraoperative radiotherapy, hadrontherapy, molecular radiotherapy, and in vivo dose monitoring. Investigations that have been performed using GEANT4 only are also mentioned to illustrate the potential of GATE. The very practical feature of GATE making it easy to model both a treatment and an imaging acquisition within the same framework is emphasized. The computational times associated with several applications are provided to illustrate the practical feasibility of the simulations using current computing facilities.

PMID:
24877844
DOI:
10.1118/1.4871617
[Indexed for MEDLINE]

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