Format

Send to

Choose Destination
Mol Oral Microbiol. 2014 Jun;29(3):99-116.

Innocent until proven guilty: mechanisms and roles of Streptococcus-Candida interactions in oral health and disease.

Abstract

Candida albicans and streptococci of the mitis group colonize the oral cavities of the majority of healthy humans. While C. albicans is considered an opportunistic pathogen, streptococci of this group are broadly considered avirulent or even beneficial organisms. However, recent evidence suggests that multi-species biofilms with these organisms may play detrimental roles in host homeostasis and may promote infection. In this review we summarize the literature on molecular interactions between members of this streptococcal group and C. albicans, with emphasis on their potential role in the pathogenesis of opportunistic oral mucosal infections.

PMID:
24877244
PMCID:
PMC4238848
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center