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Biomed Res Int. 2014;2014:186864. doi: 10.1155/2014/186864. Epub 2014 Apr 29.

A review on antibacterial, antiviral, and antifungal activity of curcumin.

Author information

1
Biomolecular Research Group, Biochemistry Program, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
2
Tropical Infectious Disease Research and Education Center (TIDREC), Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
3
Department of Chemistry, Faculty of Sciences, Guilan University, Rasht, Iran.
4
Tropical Infectious Disease Research and Education Center (TIDREC), Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia ; Persian Gulf Marine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr 3631, Iran.

Abstract

Curcuma longa L. (Zingiberaceae family) and its polyphenolic compound curcumin have been subjected to a variety of antimicrobial investigations due to extensive traditional uses and low side effects. Antimicrobial activities for curcumin and rhizome extract of C. longa against different bacteria, viruses, fungi, and parasites have been reported. The promising results for antimicrobial activity of curcumin made it a good candidate to enhance the inhibitory effect of existing antimicrobial agents through synergism. Indeed, different investigations have been done to increase the antimicrobial activity of curcumin, including synthesis of different chemical derivatives to increase its water solubility as well ass cell up take of curcumin. This review aims to summarize previous antimicrobial studies of curcumin towards its application in the future studies as a natural antimicrobial agent.

PMID:
24877064
PMCID:
PMC4022204
DOI:
10.1155/2014/186864
[Indexed for MEDLINE]
Free PMC Article

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