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Case Rep Oncol Med. 2014;2014:549248. doi: 10.1155/2014/549248. Epub 2014 Apr 30.

Rapidly progressed primary intestinal follicular lymphoma with elevation of soluble interleukin-2 receptor levels.

Author information

1
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
2
Department of Internal Medicine, Tsuyama Chuo Hospital, Tsuyama 708-0841, Japan.
3
Department of Pathology, Tsuyama Chuo Hospital, Tsuyama 708-0841, Japan.
4
Department of Internal Medicine, Okayama Medical Center, Okayama 701-1192, Japan.
5
Department of Endoscopy, Okayama University Hospital, Okayama 700-8558, Japan.
6
Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.

Abstract

A 62-year-old Japanese male was diagnosed with primary intestinal follicular lymphoma involving the duodenum, jejunum, and rectum without lymph node involvement. The patient was classified as low risk by the follicular lymphoma international prognostic index (FLIPI) system. Treatment was deferred because he had no symptoms. Eleven months after the diagnosis, his soluble interleukin-2 receptor (sIL-2R) levels had risen from 383 to 617 U/mL. Lymphoma progression involving an enlarged perigastric lymph node was also documented. This report illustrates a case of rapidly progressed intestinal follicular lymphoma, suggesting the possible usefulness of sIL-2R levels as an indicator of lymphoma progression.

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