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Pan Afr Med J. 2013 Nov 17;16:103. doi: 10.11604/pamj.2013.16.103.2143. eCollection 2013.

Human brucellosis: seroprevalence and associated exposure factors among abattoir workers in Abuja, Nigeria - 2011.

Author information

1
Nigeria Field Epidemiology and Laboratory Training Programme (NFELTP), Abuja, Nigeria.
2
Department of Veterinary Public Health and Preventive Medicine, Ahmadu Bello University, Zaria, Nigeria.
3
Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort 0110, South Africa and National Veterinary Research Institute, Vom, Nigeria.
4
Department of Community Medicine, Ahmadu Bello University, Zaria, Nigeria.
5
Global Public Health Solutions, Atlanta, USA.

Abstract

INTRODUCTION:

Brucellosis, a neglected debilitating zoonosis, is a recognized occupational hazard with a high prevalence in developing countries. Transmission to humans can occur through contact with infected animals or animal products. Brucellosis presents with fever. In Nigeria, there is a possibility of missed diagnoses by physicians leading to a long debilitating illness. We conducted a study to determine the seroprevalence and factors associated with Human Brucellosis (HB) among abattoir-workers in Abuja, Nigeria.

METHODS:

We conducted a cross-sectional study and selected abattoir-workers using stratified random sampling. Structured questionnaires were used to collect data on demographics and exposure-factors. We tested the workers' serum-samples using Rose-Bengal (RBPT) and ELISA tests. A worker with HB was one whose serum tested positive to RBPT or ELISA. We tested differences in proportions between workers with HB and those without HB using odds-ratio and X(2) tests.

RESULTS:

Of 224 workers, 172 (76.8%) were male and mean age was 30 + 9.0 years. Of 224 sera collected, 54 were positive giving a seroprevalence of 24.1%. Of these, 32 (59.3%) were butchers, and 11 (20.4%) were meat-sellers. Slaughtering animals while having open-wounds (Odds-ratio (OR) = 2.15, 95% Confidence Interval (CI) = 1.15-4.04); occupational-exposure of >5years (OR = 2.30, CI = 1.11-4.78) and eating raw meat (OR = 2.75, CI = 1.21-6.26) were significantly associated with HB. Multivariate analyses showed that occupational-exposure of >5years (Adjusted OR (AOR) =2.45, CI = 1.15 - 5.30) and eating raw-meat (AOR = 2.64, CI = 1.14 - 6.14) remained significantly associated with HB.

CONCLUSION:

Seroprevalence of HB among abattoir-workers in Abuja was high. Factors associated with HB were occupational-exposure of >5years and eating raw-meat. Abattoir-workers should be discouraged from eating raw-meat and educated on adherence to safe animal-product handling practices.

KEYWORDS:

Brucellosis; Nigeria; abattoir; exposure factors; occupational hazard; seroprevalence

PMID:
24876892
PMCID:
PMC4033582
DOI:
10.11604/pamj.2013.16.103.2143
[Indexed for MEDLINE]
Free PMC Article

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