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Aging Male. 2015 Jun;18(2):118-23. doi: 10.3109/13685538.2014.922532. Epub 2014 May 28.

Male breast cancer: clinical-epidemiological characteristics of 1189 Brazilian patients.

Author information

1
Clinical Research and Technology Incorporation Coordination by Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) , Rio de Janeiro (RJ) , Brazil .

Abstract

PURPOSE:

To describe the clinical-epidemiological features of male patients with breast cancer in Brazil.

METHODS:

Data from male patients with breast cancer treated from 2000 through 2009 were obtained from the Brazilian Hospital Cancer Register databases. Descriptive statistics were performed.

RESULTS:

A total of 1189 male patients were included. The mean age at diagnosis was 59.6 years (± 13.6). Tumours were categorised as clinical stage I (14.3%), stage II (38.3%), stage III (34.1%) and stage IV (13.3%). The most frequent histological type was invasive ductal carcinoma (83.7%). The first course treatment (alone or combined) consisted of chemotherapy in 53.2%, surgery in 49.2, radiation therapy in 36.8 and hormonal therapy in 21.0%; 3.4% of cases did not receive treatment. Treatment modality varies according to the tumor-node-metastasis (TNM) stage. The inadequate response rate was 15.9%, and 7.4% of patients died after the first course of treatment. Adequate response according to the first-course cancer treatment, after adjusted for clinical stage, was associated with being Caucasian (odds ratio (OR) = 2.50; 95% confidence interval (95% CI): 1.35-4.65) and submitted to chemotherapy (OR = 0.46; 95% CI: 0.28-0.74).

CONCLUSIONS:

Male breast cancer diagnosis is often made in the advanced stage. Consequently, patients were subjected to more aggressive treatments, with poorer clinical response.

KEYWORDS:

Clinical characteristics; male breast cancer; treatment

PMID:
24871582
DOI:
10.3109/13685538.2014.922532
[Indexed for MEDLINE]

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