Abstract
Thiazide-type diuretics frequently produce erectile dysfunction in men on a regular diet. However, men on a weight-loss diet have much less erectile dysfunction. Thiazide-type diuretics also produce erectile dysfunction in rats and interfere with normal copulation. The mechanism of the dysfunction and the favorable response to weight loss is unknown.
Publication types
-
Clinical Trial
-
Randomized Controlled Trial
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Animals
-
Benzothiadiazines*
-
Diuretics
-
Drug Evaluation, Preclinical
-
Humans
-
Hypertension / diet therapy
-
Hypertension / drug therapy
-
Libido / drug effects
-
Male
-
Penile Erection / drug effects*
-
Rats
-
Sexual Dysfunction, Physiological / chemically induced
-
Sexual Dysfunction, Physiological / prevention & control
-
Sodium Chloride Symporter Inhibitors / adverse effects*
-
Weight Loss*
Substances
-
Benzothiadiazines
-
Diuretics
-
Sodium Chloride Symporter Inhibitors