Format

Send to

Choose Destination
Trends Cogn Sci. 2014 Jul;18(7):351-63. doi: 10.1016/j.tics.2014.03.008. Epub 2014 May 23.

Topographic organization in the brain: searching for general principles.

Author information

1
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA; New York State Psychiatric Institute, New York, NY 10032, USA. Electronic address: patelga@nyspi.columbia.edu.
2
Department of Cognitive Science, Macquarie University, Sydney, NSW 2109, Australia.
3
Department of Anatomy and Neurobiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.

Abstract

The neurons comprising many cortical areas have long been known to be arranged topographically such that nearby neurons have receptive fields at nearby locations in the world. Although this type of organization may be universal in primary sensory and motor cortex, in this review we demonstrate that associative cortical areas may not represent the external world in a complete and continuous fashion. After reviewing evidence for novel principles of topographic organization in macaque lateral intraparietal area (LIP) - one of the most-studied associative areas in the parietal cortex - we explore the implications of these new principles for brain function.

PMID:
24862252
PMCID:
PMC4074559
DOI:
10.1016/j.tics.2014.03.008
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center