Effects of fluazuron (2.5 mg/kg) and a combination of fluazuron (3.0 mg/kg) + abamectin (0.5 mg/kg) on the reproductive parameters of a field population of Rhipicephalus (Boophilus) microplus on experimentally infested cattle

Res Vet Sci. 2014 Aug;97(1):80-4. doi: 10.1016/j.rvsc.2014.04.012. Epub 2014 May 5.

Abstract

The current study assessed the deleterious effects of two formulations of fluazuron (2.5 mg/kg fluazuron and a combination of 3.0 mg/kg fluazuron + 0.5 mg/kg abamectin) on the reproductive parameters of engorged Rhipicephalus (Boophilus) microplus females that naturally detached from experimentally infested cattle in two experiments. Based on the obtained results, it can be concluded that fluazuron (2.5 mg/kg) showed deleterious effects only on the hatchability percentage in the period of 2-7 post-treatment days of this ectoparasite's engorged females. On the other hand, the fluazuron (3.0 mg/kg) + abamectin (0.5 mg/kg) combination presented harmful effects over reproductive parameters of this tick species. Further studies should be performed with a known tick population (reference susceptible strain) to determine the effect of these formulations on the reproductive parameters and to elucidate if this field population is fluazuron resistant.

Keywords: Abamectin; Engorged females; Fluazuron; Reproductive parameters; Rhipicephalus (Boophilus) microplus.

Publication types

  • Clinical Trial

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / drug therapy*
  • Cattle Diseases / parasitology*
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Female
  • Insecticides / administration & dosage*
  • Ivermectin / administration & dosage
  • Ivermectin / analogs & derivatives*
  • Phenylurea Compounds / administration & dosage*
  • Reproduction / drug effects
  • Rhipicephalus / drug effects*
  • Skin Diseases, Parasitic / drug therapy
  • Skin Diseases, Parasitic / veterinary*
  • Tick Infestations / drug therapy
  • Tick Infestations / veterinary*

Substances

  • Insecticides
  • Phenylurea Compounds
  • abamectin
  • Ivermectin
  • fluazuron