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J Gerontol A Biol Sci Med Sci. 2014 Jun;69 Suppl 1:S1-3. doi: 10.1093/gerona/glu041.

Advances in geroscience: impact on healthspan and chronic disease.

Author information

1
Center for Scientific Review, National Institutes of Health, Bethesda, Maryland.
2
Immunoregulation Section, Basic Immunology Branch, Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
3
Research Training and Career Development Branch, National Institute of Dental and Craniofacial Research, Bethesda, Maryland.
4
Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, Maryland.
5
National Cancer Institute, NIH, Division of Cancer Biology, Bethesda, Maryland.
6
Cancer Etiology Branch, DNA and Chromosome Aberrations Branch, Division of Cancer Biology, National Cancer Institute, Bethesda, Maryland.
7
Division of Extramural Research, National Center for Complementary and Alternative Medicine, Bethesda, Maryland.
8
Division of Aging Biology, National Institute on Aging, Bethesda, Maryland. kohanskir@mail.nih.gov.
9
Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
10
Radiation and Nuclear Countermeasures, Program Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
11
Geriatrics and Aging Processes Research Branch, National Institute of Mental Health, Bethesda, Maryland.
12
Vascular Biology and Hypertension Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland.
13
Pharmacogenomics and Drug Discovery, National Institute of Diabetes and Digestive and Kidney Diseases, Division of Diabetes, Endocrinology, and Metabolic Diseases, Bethesda, Maryland.
14
Office of Cancer Clinical Proteomics Research, Office of the Director and.
15
Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland.
16
Retinal Diseases Program, Division of Extramural Research, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
17
Division of Aging Biology and.
18
Neurobiology of Aging Branch, Division of Neuroscience, National Institute on Aging, Bethesda, Maryland.

Abstract

Population aging is unprecedented, without parallel in human history, and the 21st century will witness even more rapid aging than did the century just past. Improvements in public health and medicine are having a profound effect on population demographics worldwide. By 2017, there will be more people over the age of 65 than under age 5, and by 2050, two billion of the estimated nine billion people on Earth will be older than 60 (http://unfpa.org/ageingreport/). Although we can reasonably expect to live longer today than past generations did, the age-related disease burden we will have to confront has not changed. With the proportion of older people among the global population being now higher than at any time in history and still expanding, maintaining health into old age (or healthspan) has become a new and urgent frontier for modern medicine. Geroscience is a cross-disciplinary field focused on understanding the relationships between the processes of aging and age-related chronic diseases. On October 30-31, 2013, the trans-National Institutes of Health GeroScience Interest Group hosted a Summit to promote collaborations between the aging and chronic disease research communities with the goal of developing innovative strategies to improve healthspan and reduce the burden of chronic disease.

KEYWORDS:

Chronic disease; Geroscience.

PMID:
24833579
PMCID:
PMC4036419
DOI:
10.1093/gerona/glu041
[Indexed for MEDLINE]
Free PMC Article

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