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J Clin Microbiol. 2014 Nov;52(11):3839-44. doi: 10.1128/JCM.00971-14. Epub 2014 May 14.

Extraintestinal microsporidiosis.

Author information

1
Division of Infectious diseases, Mayo Clinic Health System-Eau Claire, Eau Claire, Wisconsin, USA.
2
Division of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota, USA Pritt.Bobbi@mayo.edu.

Abstract

Microsporidia are highly specialized obligate intracellular organisms that are closely related to fungi. Although traditionally associated with diarrheal illness in patients with AIDS, extraintestinal infections involving various organs have been reported with increasing frequency in the past decade, particularly in immunocompromised hosts. Diagnosis is usually accomplished by light microscopic identification of spores in body fluids and tissues, using a variety of stains. Transmission electron microscopy, immunofluorescence assays, or molecular methods are necessary for identification to the genus and species level. Early diagnosis is essential for preventing the significant associated morbidity and mortality of extraintestinal microsporidiosis.

PMID:
24829239
PMCID:
PMC4313212
DOI:
10.1128/JCM.00971-14
[Indexed for MEDLINE]
Free PMC Article

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