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Ann N Y Acad Sci. 2014 May;1318:32-40. doi: 10.1111/nyas.12452. Epub 2014 May 14.

When and for how long should glucocorticoids be used in rheumatoid arthritis? International guidelines and recommendations.

Author information

1
Department of Rheumatology, Nîmes University Hospital, Montpellier 1 University, Nîmes, France.

Abstract

Glucocorticoids are widely used in rheumatoid arthritis (RA); however, their effectiveness and safety is still a subject of debate. In particular, when to introduce glucocorticoids, but also when and how to taper them, are important questions for clinicians. In this paper, we will discuss the place of glucocorticoids in the European League Against Rheumatism (EULAR) recommendations for the management of RA and review the literature that was the basis for these recommendations. The recommendations cover the introduction of glucocorticoids (and for whom they are recommended), doses and duration of treatment, and tapering strategies. Items still on the research agenda include more data on safety, particularly for long-term use, and small doses of glucocorticoids.

KEYWORDS:

EULAR; glucocorticoids; inflammation; recommendations; rheumatoid arthritis

PMID:
24827544
DOI:
10.1111/nyas.12452
[Indexed for MEDLINE]

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