Format

Send to

Choose Destination
See comment in PubMed Commons below
J Venom Anim Toxins Incl Trop Dis. 2014 May 6;20:19. doi: 10.1186/1678-9199-20-19. eCollection 2014.

Septic arthritis: immunopathogenesis, experimental models and therapy.

Author information

1
Departamento de Microbiologia e Imunologia, Instituto de Biociências, Universidade Estadual Paulista (UNESP), Distrito de Rubião Júnior, s/n, Botucatu, São Paulo State, Brazil.

Abstract

Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included.

KEYWORDS:

Mice; Septic arthritis; Staphylococcus aureus

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Support Center