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Ear Nose Throat J. 2014 Apr-May;93(4-5):E16-20.

Endoscopic transnasal transsphenoidal approach for craniopharyngioma: report of 6 cases.

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Department of Otolaryngology-Head and Neck Surgery, St. Vincent's Hospital, Suwon City, Korea.


We conducted a retrospective study to evaluate outcomes in patients with a craniopharyngioma who were managed via a transnasal transsphenoidal approach. Craniopharyngiomas exhibit histologically benign but "clinically malignant" features. Our study group was made up of 5 patients who underwent a total of 6 operations. The study population included 1 female and 5 males, aged 14 to 50 years (mean: 29.2). The overall rate of near-total tumor removal was 67%, but all patients eventually experienced a recurrence. Revision surgery to correct any severe postoperative complications was not required in any case. We found that the endoscopic transnasal transsphenoidal approach could be a safe and less invasive surgical option for the removal of craniopharyngiomas, although we were unable to remove all tumor or prevent recurrences.

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