Send to

Choose Destination
See comment in PubMed Commons below
J Clin Psychiatry. 2014 Apr;75(4):e10. doi: 10.4088/JCP.13010tx2c.

Acute and maintenance treatments for bipolar depression.

Author information

From the Department of Psychiatry and Behavioral Sciences and the Bipolar Disorders Clinic, Stanford School of Medicine, Stanford, California.


Patients with bipolar disorder are symptomatic about half of the time, experiencing depression more often than mania/hypomania. Because patients usually seek treatment during a depressive episode (rather than a manic episode), bipolar depression is commonly misdiagnosed as unipolar depression. Providing an accurate and timely bipolar depression diagnosis is critical for the proper treatment of the patient. Some FDA-approved treatments are helpful during acute and maintenance phases of therapy, but there is a significant unmet need for effective bipolar depression treatments with favorable side-effect profiles. Newer agents offer the promise of improvements in tolerability, but additional research is needed to actualize this promise into better treatments for patients struggling with bipolar depression.

[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Physicians Postgraduate Press, Inc.
    Loading ...
    Support Center