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Nature. 1989 Dec 14;342(6251):762-6.

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel.

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1
Department of Medical Chemistry, Kyoto University Faculty of Medicine, Japan.

Abstract

The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photoreceptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains several putative transmembrane segments, followed by a region that is similar to the cyclic GMP-binding domains of cyclic GMP-dependent protein kinase. Expression of the complementary DNA produces cyclic GMP-gated channel activity in Xenopus oocytes.

PMID:
2481236
DOI:
10.1038/342762a0
[Indexed for MEDLINE]
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