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Int J Pediatr Otorhinolaryngol. 2014 Jul;78(7):1115-8. doi: 10.1016/j.ijporl.2014.04.026. Epub 2014 May 5.

The effectiveness of nasal saline irrigation (seawater) in treatment of allergic rhinitis in children.

Author information

1
Department of Otolaryngology-Head and Neck Surgery, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China.
2
Department of Otolaryngology-Head and Neck Surgery, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China. Electronic address: chhshent@163.com.

Abstract

OBJECTIVE:

To evaluate the effect of nasal saline irrigation in the treatment of allergic rhinitis (AR) in children and to assess whether nasal saline irrigation could be used as a complementary therapy for AR in children in combination with the intranasal corticosteroids (INS).

METHOD:

In total, 61 children with AR were divided into three groups: the nasal irrigation, intranasal corticosteroid, and combined treatment groups. Symptoms and signs of AR and eosinophils (EOS) in the nasal secretions were evaluated after 4 weeks, 8 weeks, and 12 weeks of treatment.

RESULTS:

In AR children treated with nasal irrigation and a decreased the INS dose, a significant improvement in symptoms and signs and a significant decrease in the mean EOS count in nasal secretions were observed at week 12.

CONCLUSION:

Nasal saline irrigation with physiological seawater is well tolerated and benefits the patients with AR, and can thus be considered a good adjunctive treatment option to maintain the effectiveness of the INS at a lower dose, thus resulting in reduced side effects and a decreased economic burden.

KEYWORDS:

Allergic rhinitis; Intranasal corticosteroids; Nasal saline irrigation; Seawater

PMID:
24809770
DOI:
10.1016/j.ijporl.2014.04.026
[Indexed for MEDLINE]
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