Format

Send to

Choose Destination
Diabetes Care. 2014 Aug;37(8):2240-5. doi: 10.2337/dc13-2267. Epub 2014 May 7.

Life's Simple 7 and incidence of diabetes among American Indians: the Strong Heart Family Study.

Author information

1
Department of Epidemiology, University of Washington, Seattle, WACardiovascular Health Research Unit, University of Washington, Seattle, WA amfretts@u.washington.edu.
2
MedStar Health Research Institute, Washington, DCGeorgetown and Howard Universities Center for Clinical and Translational Research, Washington, DC.
3
Cardiovascular Health Research Unit, University of Washington, Seattle, WADepartment of Biostatistics, University of Washington, Seattle, WA.
4
Department of Epidemiology, University of Washington, Seattle, WA.
5
MedStar Health Research Institute, Washington, DC.
6
Center for American Indian Health Research, University of Oklahoma, Oklahoma City, OK.
7
Department of Epidemiology, University of Washington, Seattle, WACardiovascular Health Research Unit, University of Washington, Seattle, WADepartment of Medicine, University of Washington, Seattle, WA.

Abstract

OBJECTIVE:

The American Heart Association's recommendations for optimal health, summarized in Life's Simple 7, have been associated with reduced risk of cardiovascular disease (CVD)-related end points, but no studies have examined the association of these goals with incident type 2 diabetes, which is associated with high risk for CVD. The purpose of this analysis was to examine the associations of Life's Simple 7 goals with incident diabetes among American Indians, a population at high risk of cardiometabolic diseases.

RESEARCH DESIGN AND METHODS:

Strong Heart Family Study participants without diabetes (n = 1,639) at baseline and who participated in a follow-up examination were included in the analysis. Risk scores ranging from 0 to 7 were created using physical activity, diet, BMI, smoking, blood pressure, fasting glucose, and cholesterol metrics in accordance with Life's Simple 7 goals. Diabetes was defined using 2003 American Diabetes Association criteria, including use of insulin or oral antidiabetes medication or a follow-up fasting plasma glucose level ≥126 mg/dL. Generalized estimating equations were used to examine the association of risk scores with incident diabetes.

RESULTS:

During a mean 5-year follow-up (range 4-8 years), we identified 210 cases of incident type 2 diabetes. Compared with participants who achieved 0-1 goals, those who achieved 2-3 or 4+ goals had lower odds of diabetes, with odds ratios = 0.40 (95% CI 0.29-0.56) and 0.11 (95% CI 0.05-0.21), respectively.

CONCLUSIONS:

The adoption of as few as two or three Life's Simple 7 goals is associated with a lower risk of diabetes.

PMID:
24804696
PMCID:
PMC4113167
DOI:
10.2337/dc13-2267
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center