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Eur J Pediatr. 1989 Nov;149(2):76-9.

Somatomedin-binding proteins: what role do they play in the growth process?

Author information

1
Department of Paediatrics, Tor Vergata University Medical School, II University of Rome, Italy.

Abstract

The insulin-like growth factors (IGF-I and IGF-II) circulate bound to specific proteins. Two classes of binding proteins have been relatively well characterized differing in size, immunological activity, and physiological function. This review summarizes the more recent data on IGF-binding proteins, focusing on their possible clinical implications.

PMID:
2480240
[Indexed for MEDLINE]

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