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Curr Biol. 2014 May 5;24(9):R368-70. doi: 10.1016/j.cub.2014.03.046.

Sex: how malaria parasites get turned on.

Author information

1
Harvard School of Public Health, Department of Immunology and Infectious Diseases, 665 Huntington Ave, Boston, MA 02115, USA.
2
Harvard School of Public Health, Department of Immunology and Infectious Diseases, 665 Huntington Ave, Boston, MA 02115, USA. Electronic address: mmarti@hsph.harvard.edu.

Abstract

The mechanisms underlying sexual stage switching in Plasmodium spp. have hitherto remained a mystery. However, two recent studies have revealed that an apicomplexan-specific DNA-binding protein is essential for the initiation of this cell fate decision, ultimately providing the malaria community with a novel and important tool in the battle to prevent malaria transmission.

PMID:
24801188
DOI:
10.1016/j.cub.2014.03.046
[Indexed for MEDLINE]
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