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Front Microbiol. 2014 Apr 22;5:174. doi: 10.3389/fmicb.2014.00174. eCollection 2014.

Metabolic engineering of yeasts by heterologous enzyme production for degradation of cellulose and hemicellulose from biomass: a perspective.

Author information

  • 1School of Genetics and Microbiology, Department of Microbiology, Trinity College Dublin Dublin, Ireland.

Abstract

This review focuses on current approaches to metabolic engineering of ethanologenic yeast species for the production of bioethanol from complex lignocellulose biomass sources. The experimental strategies for the degradation of the cellulose and xylose-components of lignocellulose are reviewed. Limitations to the current approaches are discussed and novel solutions proposed.

KEYWORDS:

cellulases; recombinant yeasts; xylose-utilizing enzymes

PMID:
24795706
PMCID:
PMC4001029
DOI:
10.3389/fmicb.2014.00174

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