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J Neurol Sci. 2014 Jun 15;341(1-2):165-6. doi: 10.1016/j.jns.2014.04.013. Epub 2014 Apr 18.

Opsoclonus-myoclonus syndrome associated with human herpes virus-6 rhomboencephalitis.

Author information

1
Neurology Unit, Department of Medicine, S. Anna Hospital, Como, Italy. Electronic address: vincenzobelcastro@libero.it.
2
Neurology Unit, Department of Medicine, S. Anna Hospital, Como, Italy.
3
Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
4
Department of Medicine, S. Anna Hospital, Como, Italy.

Abstract

Opsoclonus-myoclonus syndrome (OMS) is characterized by opsoclonus and arrhythmic-action myoclonus that predominantly involves the trunk, limbs, and head. Human herpes virus-6 (HHV-6) can rarely cause encephalitis in immunocompetent children and adults. Here we report on a case of OMS associated with HHV-6 rhomboencephalitis. HHV-6 infection should be considered in OMS adults and detection of cell-free viral DNA, indicative of active infection, is mandatory in such cases.

KEYWORDS:

Human herpes virus-6 infection; Opsoclonus–myoclonus syndrome; Rhomboencephalitis

PMID:
24793510
DOI:
10.1016/j.jns.2014.04.013
[Indexed for MEDLINE]

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