Drug-induced peripheral neuropathy

Ole Jakob Vilholm; Alex Alban Christensen; Ahmed Hussein Zedan; Mustapha Itani

doi:10.1111/bcpt.12261

Drug-induced peripheral neuropathy

Basic Clin Pharmacol Toxicol. 2014 Aug;115(2):185-92. doi: 10.1111/bcpt.12261. Epub 2014 May 20.

Authors

Ole Jakob Vilholm¹, Alex Alban Christensen, Ahmed Hussein Zedan, Mustapha Itani

Affiliation

¹ Department of Neurology, Lillebaelt Hospital, Vejle, Denmark.

PMID: 24786912
DOI: 10.1111/bcpt.12261

Abstract

Peripheral neuropathy can be caused by medication, and various descriptions have been applied for this condition. In this MiniReview, the term 'drug-induced peripheral neuropathy' (DIPN) is used with the suggested definition: Damage to nerves of the peripheral nervous system caused by a chemical substance used in the treatment, cure, prevention or diagnosis of a disease. Optic neuropathy is included in this definition. A distinction between DIPN and other aetiologies of peripheral neuropathy is often quite difficult and thus, the aim of this MiniReview is to discuss the major agents associated with DIPN.

Publication types

Review

MeSH terms

Drug-Related Side Effects and Adverse Reactions / etiology
Drug-Related Side Effects and Adverse Reactions / physiopathology*
Humans
Optic Nerve Diseases / chemically induced
Optic Nerve Diseases / pathology
Peripheral Nerves / drug effects*
Peripheral Nerves / physiopathology
Peripheral Nervous System Diseases / chemically induced*
Peripheral Nervous System Diseases / physiopathology