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Clin Infect Dis. 2014 Aug 1;59(3):401-3. doi: 10.1093/cid/ciu302. Epub 2014 Apr 29.

High colonization rate and prolonged shedding of Clostridium difficile in pediatric oncology patients.

Author information

1
Department of Pediatric Infectious Diseases Department of Epidemiology.
2
Department of Epidemiology.
3
Epidemic Intelligence Service Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
4
Epidemic Intelligence Service Colorado Department of Public Health and Environment, Denver.
5
Department of Pediatric Hematology/Oncology/Bone Marrow Transplant Department of Nursing.
6
Department of Pathology and Laboratory Medicine.
7
Department of Adult Infectious Diseases, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora.
8
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
9
Department of Pediatric Hematology/Oncology/Bone Marrow Transplant.

Abstract

Surveillance testing for Clostridium difficile among pediatric oncology patients identified stool colonization in 29% of patients without gastrointestinal symptoms and in 55% of patients with prior C. difficile infection (CDI). A high prevalence of C. difficile colonization and diarrhea complicates the diagnosis of CDI in this population.

KEYWORDS:

Clostridium difficile; colonization; oncology; pediatric; surveillance

PMID:
24785235
DOI:
10.1093/cid/ciu302
[Indexed for MEDLINE]
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