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J Clin Apher. 2015 Feb;30(1):46-9. doi: 10.1002/jca.21325. Epub 2014 Apr 30.

Successful management of thrombotic thrombocytopenic purpura in a Jehovah's Witness without plasma exchange.

Author information

1
Department of Internal Medicine, Lahey Hospital and Medical Center, Burlington, Massachusetts.

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a hematologic emergency characterized by microangiopathic hemolytic anemia and thrombocytopenia. Plasma exchange is the standard treatment. Treating TTP without plasma exchange is a challenge. Due to religious beliefs, Jehovah's Witnesses do not accept transfusions of blood products. We report a case of successful treatment of TTP in a Jehovah's Witness using plasma exchange with albumin replacement.

KEYWORDS:

Jehovah's Witness; corticosteroid; plasma-free exchange; rituximab; thrombotic thrombocytopenic purpura

PMID:
24782109
DOI:
10.1002/jca.21325
[Indexed for MEDLINE]

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