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Worm. 2013 Jul 1;2(3):e25546. doi: 10.4161/worm.25546. Epub 2013 Jul 12.

Complex RIA calcium dynamics and its function in navigational behavior.

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Harvard University; Department of Organismic and Evolutionary Biology; Center for Brain Science; Cambridge, MA USA.


Recently, we have reported novel and complex calcium dynamics in the RIA interneuron, which has been implicated in several navigational behaviors in C. elegans. Here, we review our findings on the compartmentalized and global calcium events in RIA and propose functional consequence as well as potential regulatory mechanisms of these intriguing calcium signals.


acetylcholine signaling; compartmental calcium signal; corollary discharge; global calcium signal; regulation of navigation; wiring diagram

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