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Brain Stimul. 2014 Jul-Aug;7(4):521-4. doi: 10.1016/j.brs.2014.03.009. Epub 2014 Mar 30.

Clinician accessible tools for GUI computational models of transcranial electrical stimulation: BONSAI and SPHERES.

Author information

1
Department of Biomedical Engineering, The City College of New York, City University of New York, New York, NY, USA. Electronic address: dtruong01@ccny.cuny.edu.
2
Department of Biomedical Engineering, The City College of New York, City University of New York, New York, NY, USA.
3
Soterix Medical Inc., New York, NY, USA.

Abstract

Computational models of brain current flow during transcranial electrical stimulation (tES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), are increasingly used to understand and optimize clinical trials. We propose that broad dissemination requires a simple graphical user interface (GUI) software that allows users to explore and design montages in real-time, based on their own clinical/experimental experience and objectives. We introduce two complimentary open-source platforms for this purpose: BONSAI and SPHERES. BONSAI is a web (cloud) based application (available at neuralengr.com/bonsai) that can be accessed through any flash-supported browser interface. SPHERES (available at neuralengr.com/spheres) is a stand-alone GUI application that allow consideration of arbitrary montages on a concentric sphere model by leveraging an analytical solution. These open-source tES modeling platforms are designed go be upgraded and enhanced. Trade-offs between open-access approaches that balance ease of access, speed, and flexibility are discussed.

KEYWORDS:

Dose; Modeling; Open access; Transcranial alternating current stimulation; Transcranial direct current stimulation; Transcranial electrical stimulation

PMID:
24776786
PMCID:
PMC4108562
DOI:
10.1016/j.brs.2014.03.009
[Indexed for MEDLINE]
Free PMC Article

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