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Rev Esp Cardiol (Engl Ed). 2014 Apr;67(4):259-69. doi: 10.1016/j.rec.2013.07.014. Epub 2013 Nov 25.

Prevalence of atrial fibrillation in Spain. OFRECE study results.

Collaborators (482)

Gómez-Doblas JJ, Muñiz J, Martín JJ, Roig E, Rodríguez-Roca G, Lobos JM, Permanyer G, Anguita M, Gil JB, Montero FG, Pereira CM, Fábrega L, Flores FJ, García EC, Robles JE, López MG, Ruiz MR, Deudero JC, Mateos IP, Conejo JR, Fuentes-Guerra DM, Morales MO, de Lara Muñoz R, López MP, Campoo FU, Sánchez JM, Sánchez MA, Criado EG, Martínez J, Sánchez JR, Rioboo EM, Barranco JM, Moruno FJ, Espejo MA, Taberne CA, Gallego JJ, Espino AC, Frías PT, Bueno RL, Martín AC, Serrano CM, Paredes PT, Larroque AM, Martín AA, Marcos AM, González CS, Carpio AO, Fortes M, García JF, Cumplido IR, Pérez PF, de Castroviejo EV, Tejero RA, Sánchez FB, Povedano PT, Andreu LE, Cardona VF, Milena AP, Martínez JM, Serrano M, Carmona JR, Ramírez AA, Camañes CG, Criado CC, Utrera CD, Galán DM, Gutiérrez IB, Bueno JL, Jiménez VV, Martínez VA, Gallego BP, Ortigosa JM, Pérez VR, López AM, Gallardo AC, Villanueva JE, Torrente MR, Joven EA, Martínez JM, Marco JM, Rodríguez DI, Aznar TL, Fuertes AR, Velasco CQ, Arenaz CA, Navascues JM, Olivera JM, Ciria G, Gayán R, Terrón AA, Arribas M, Velázquez PJ, Jiménez AB, Arévalo RV, Pina JF, Ladrero R, Lozano M, García JJ, Moreno JM, Hernández M, Varela MB, Cocina AJ, González FJ, Fernández NJ, Gutiérrez JP, Hernández AS, González PS, de Ubago AP, Ruiz MB, Verdú AC, Vizcaíno CE, Ayllón FJ, Salido FL, García CM, Moragón MC, Lozano AM, López JM, Carretero MM, Herrero LR, García RB, Cornejo M, Serrano CH, Ruiz AG, Canales AH, Serrano AL, Sánchez AF, García-Rojo AR, Sánchez M, Pita AM, Polo IS, Ramilo RM, Villar JR, López FM, Sánchez AC, Serrano RM, Bermejo JB, Santos SS, Saiz AR, Lezana JM, Padial LR, Míguez RP, Díaz JI, Alía AA, Martín AS, Escudero MV, Peralta ML, Rodríguez JM, Valero M, Moreno FJ, López CR, Giner IM, Hernández JA, Malabia MD, Acosta VM, Puente IM, Gutiérrez MA, de Cabo González C, Jiménez LS, Almarza F, Delgado BN, Hernández CR, Gómez CJ, Clavo JL, Picón AC, Martín BS, Ojeda GP, Movilla AM, Recansens PL, Bernabe LA, Abad CC, Cuadrillero JG, Caballero M, Mozo BS, Rosón FE, González M, Orcajo NA, de Blas RC, Vicente CP, Blanco AR, Santín LM, Marassa M, de Celis MG, Mielgo EF, Sanmartino FS, de la Varga MG, Mato AN, Marín AI, Berceruelo JM, Guillén CA, Sánchez JA, Eguiluz JL, González MC, de Inés Martín E, Elices JM, Cacharro JM, Benito TM, García IA, Laguna M, Candil JJ, Izquierdo JG, del Olmo JG, Ortiz LG, Leal CH, Becerro JC, de Antonio Jiménez C, Cereceda MB, Planas CJ, Ortega EG, Teresa RM, Manrique M, García JF, Segovia MM, Quirós FM, Perlado JG, Cecilia AI, de Pablo Álamo J, de Pablo Ramos M, Puente AM, Caballero M, Gómez AA, Sanz FJ, Moreno LG, de Pablo Ramos E, Martínez RG, Esteban AL, Molinos GB, Gómez MJ, Velasco R, de la Fuente M, García JM, Vicente VC, Ramón EG, Oteruelo LA, Rodríguez JF, Monedero ES, Sanz R, Torres MA, de Murua López JA, Ramos AN, Rodríguez FJ, Gutiérrez LG, Enríquez AR, Martín M, Martín PM, Ramos CP, Mantellán MP, Panero GG, Meléndez AJ, Auñón AÁ, Loidi VB, Flores SS, Salvador JN, Domínguez ME, Vicentín TC, Quílez FJ, Fernández FJ, Gete LD, Muntané AM, Santana AE, Roselló AL, García M, Echevarria JN, Millán M, Lizondo HM, Vilalta MR, Montero JS, Yubero JG, Granados FC, Clos ML, Segarra EM, Bosch RC, Sanmartín CL, Parramón D, de Carlos BS, Batlle CS, Garanger JP, Fernández LV, Diz FW, González JS, Bravo MO, Rosich AR, Soler PS, Pujol EP, Jove JM, Serra JL, Queiruga OP, Blanco AV, Klein JM, Viñes MP, Serrano ES, Luján FM, Ibáñez RM, Lluis RA, Ruiz FG, Palacios IP, Soler DG, Fort AC, Tomás MC, Santafe RG, Moreno NG, Martínez SP, Bevia SG, Rodríguez LR, Aznar AA, Adán MA, Rubio LF, Ballestar JV, Sánchez BS, Aguilera AA, Costa M, Sales MB, Giner MI, Arnau MT, Pinto M, Fort M, Monedero M, Soriano FR, Añón FQ, Miquel JC, Juanola M, Villalba MT, Lorente AC, Herrera AM, Martín JJ, Concellón AG, Llinás MS, Calderón CM, Martínez M, de Entresotos BP, Ramos RT, Ruiz JA, Barrado JJ, Escanilla FP, Mateos CA, Fraile DI, Espárrago AG, Fernández M, García JP, Hernández ST, Borreguero SR, García AB, Fernández JA, Álvarez DB, Fernández LB, Saavedra FJ, Castro MB, Martínez JM, Santiago JL, Sánchez CB, Díaz CI, Fernández T, López GF, Bonome JE, Tamargo JM, Barazal CA, Madariaga VQ, Rivas DD, Méndez DF, Novo M, Teijeiro BP, García MG, Custodio RC, del Alamo Alonso AJ, Iglesias PB, Penedo AP, Novoa M, Vázquez AV, Estévez AD, Insua JL, Castiñeiras AR, Iglesias FC, Miguez EF, Sánchez JC, Núñez XF, Sabaris JJ, Panadeiros JR, Ballesteros M, Sardiña MD, Lueiro M, Martín MM, Sobrino FL, Luengos DC, Achtel NF, Vidal T, Colom AP, Vicens AJ, Ruiz CG, Yanes CP, Moreno CL, Reus FB, Delgado SM, Liste M, Alayón PJ, Muñoz LA, Sarmiento JP, López BP, Vega DG, Carrión ES, Quilez JS, González GC, Rodríguez TG, Santana CB, Hernández HP, Carrillo M, Cabrera JF, Andrés AB, Brito EN, Álvarez FJ, Llorca AB, Galán AJ, Saenz JT, Adan JM, Angos JP, Somoza AP, de Bobadilla JM, Martínez JM, Hurtado IF, Olano MU, Díaz JJ, Fernández OL, Antolín JM, Serrano AS, Gómez BM, Sacristán M, Urea RB, Giraldo M, Álvarez MN, Gómez-Calcerrada CD, Anchoriz IA, Cuadrado RV, García MV, de Casas Fernández MX, Martínez RL, Minguell AJ, Lucerga CC, Sánchez MM, López M, Martínez M, Maguel MH, García AC, Juango MA, Urabayen VE, Gómez JM, Moreno RV, Videndo M, Echeverria CF, Pascual JM, Abad AE, Burgui JJ, Mora MB, Zubiaur JA, Eguillor M, de Lazcano Herrera LO, López LP, Gainzarain MA, Landa JC, González LL, Cuadra FJ, Recalde E, Gabiola JR, García AA, Cascallana MM, Eizagaetxebarría NM, Berasategui I, Horno JB, Angulo CL, Del Pozo Yruegas JA, Errazquin AR, Angulo IA, Grande EÁ, de Soto Gorroño MN, Rivero RA, García PA, Ruigómez AC, Valera CC, Cerezuela AF, Abad CG, Hernández RM, Méndez ML, Antolín JM, Sánchez PT, Mestre RT.

Author information

1
Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain. Electronic address: jjgomezdoblas@secardiologia.es.
2
Instituto Universitario de Ciencias de la Salud, Universidad de A Coruña, A Coruña, Spain.
3
Servicio de Cardiología, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain.
4
Centro de Salud La Puebla de Montalbán, Toledo, Spain.
5
Centro de Salud Jazmín, Madrid, Spain.
6
Servicio de Cardiología, Hospital Universitario Vall d'Hebron, Barcelona, Spain.
7
Servicio de Cardiología, Hospital Clínico Universitario de Valencia, Valencia, Spain.
8
Servicio de Cardiología, Hospital Reina Sofía, Córdoba, Spain.
9
Servicio de Cardiología, Hospital de Sant Pau, Barcelona, Spain.

Abstract

INTRODUCTION AND OBJECTIVES:

Atrial fibrillation is associated with substantial morbidity and mortality and both its incidence and prevalence are high. Nevertheless, comprehensive data on this condition in Spain are lacking. The aim of this study was to estimate the prevalence of atrial fibrillation in Spain.

METHODS:

A cross-sectional study was conducted in the general Spanish population older than 40 years. Two-stage random sampling was used, in which first-stage units were primary care physicians randomly selected in every Spanish province and second-stage units were 20 randomly selected persons drawn from each participating physician's assigned population. The reported prevalence was standardized for the age and sex distribution of the Spanish population. The electrocardiogram recordings were read centrally.

RESULTS:

Overall, 8343 individuals were evaluated. The mean age was 59.2 years (95% confidence interval, 58.6-59.8 years), and 52.4% of the participants were female. The overall age-adjusted prevalence of atrial fibrillation was 4.4% (95% confidence interval, 3.8-5.1). Prevalence was similar in both sexes, men 4.4% (3.6-5.2) and women 4.5% (3.6-5.3), rising with increasing age older than 60 years. In patients older than 80 years, the prevalence was 17.7% (14.1-21.3). In 10% of patients an unknown atrial fibrillation was diagnosed.

CONCLUSIONS:

The prevalence of atrial fibrillation in the general Spanish population older than 40 years is high, at 4.4%. The prevalence is similar in both sexes and rises steeply above 60 years of age. It is estimated that there are over 1 million patients with atrial fibrillation in the Spanish population, of whom over 90,000 are undiagnosed.

KEYWORDS:

Atrial fibrillation; Epidemiology; Epidemiología; Fibrilación auricular; Prevalence; Prevalencia

PMID:
24774588
DOI:
10.1016/j.rec.2013.07.014
[Indexed for MEDLINE]

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