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Eur Arch Otorhinolaryngol. 2015 Apr;272(4):799-819. doi: 10.1007/s00405-014-3053-z. Epub 2014 Apr 26.

Salivary mucoepidermoid carcinoma revisited.

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1
Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain.

Abstract

Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.

PMID:
24771140
DOI:
10.1007/s00405-014-3053-z
[Indexed for MEDLINE]
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