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Qual Life Res. 2014 Nov;23(9):2569-75. doi: 10.1007/s11136-014-0696-6. Epub 2014 Apr 24.

Vitamin D and health-related quality of life in a community sample of older Canadians.

Author information

1
School of Public Health, University of Alberta, 3-50 University Terrace, 8303 - 112 Street, Edmonton, AB, T6G 2T4, Canada.

Abstract

PURPOSE:

To assess how vitamin D status is associated with health-related quality of life (HRQOL) among older residents of Canada.

DESIGN:

We analysed baseline data of 1,493 Canadians aged 50 years and over in Alberta on HRQOL (EQ-5D-5L) and serum 25-hydroxyvitamin D (25(OH)D) as a measure of vitamin D status. We applied multivariable regression methods to examine the association between vitamin D status and each of the five dimensions and the summary index of the EQ-5D-5L.

RESULTS:

Participants with higher serum 25(OH)D levels were significantly less likely to report problems with mobility, usual activities, and depression and anxiety. Specifically, age- and gender-adjusted odds ratios for reporting problems with mobility, usual activities, and depression and anxiety were 0.58 (95 % confidence interval 0.44-0.78), 0.67 (0.50-0.89), and 0.67 (0.51-0.88) per 100 nmol/L increase in 25(OH)D, respectively. No significant associations were observed for problems with self-care and with pain and discomfort. HRQOL scores combining the responses of each of the five dimensions increased significantly with increasing serum 25(OH)D levels.

CONCLUSIONS:

This is the first study to reveal the importance of vitamin D for the five dimensions of HRQOL in a community-based sample. The observed associations of vitamin D and HRQOL call for intervention studies to strengthen the evidence of the potential benefits of vitamin D supplementation for HRQOL among older adults.

PMID:
24760533
PMCID:
PMC4186994
DOI:
10.1007/s11136-014-0696-6
[Indexed for MEDLINE]
Free PMC Article

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