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Handb Exp Pharmacol. 2014;222:1-12. doi: 10.1007/978-3-642-54215-2_1.

TRPs: truly remarkable proteins.

Author information

1
Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, Gebäude 46, 66421, Homburg, Germany, veit.flockerzi@uks.eu.

Abstract

The family of transient receptor potential cation channels has received in the last 10 years a tremendous interest because members of this family are involved in a plethora of cell functions and have been identified as causal for many hereditary and acquired diseases. We shortly introduce these channels, summarize nomenclature and chromosomal location of the 28 mammalian Trp genes, and list the available Trp-deficient mouse lines.

PMID:
24756700
DOI:
10.1007/978-3-642-54215-2_1
[Indexed for MEDLINE]

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