Radiation recall reaction causing cardiotoxicity

J Cardiovasc Magn Reson. 2014 Apr 22;16(1):25. doi: 10.1186/1532-429X-16-25.

Abstract

Radiation recall phenomenon is a tissue reaction that develops within a previously irradiated area, precipitated by the subsequent administration of certain chemotherapeutic agents. It commonly affects the skin, but can also involve internal organs with functional consequences. To our best knowledge, this phenomenon has never been reported as a complication on the heart and should be consider as a potential cause of cardiotoxicity.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / secondary
  • Adenocarcinoma / therapy*
  • Adenocarcinoma of Lung
  • Antineoplastic Agents / adverse effects*
  • Chemoradiotherapy / adverse effects*
  • Coronary Angiography
  • Humans
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Myocarditis / diagnosis
  • Myocarditis / etiology*
  • Myocarditis / physiopathology
  • Niacinamide / adverse effects
  • Niacinamide / analogs & derivatives*
  • Phenylurea Compounds / adverse effects*
  • Positron-Emission Tomography
  • Protein Kinase Inhibitors / adverse effects*
  • Radiation Dosage
  • Radiation Injuries / diagnosis
  • Radiation Injuries / etiology*
  • Radiation Injuries / physiopathology
  • Risk Factors
  • Sorafenib
  • Whole Body Imaging

Substances

  • Antineoplastic Agents
  • Phenylurea Compounds
  • Protein Kinase Inhibitors
  • Niacinamide
  • Sorafenib