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Chem Commun (Camb). 2014 May 30;50(42):5656-8. doi: 10.1039/c4cc01855a.

Label-free detection of C-reactive protein using highly dispersible gold nanoparticles synthesized by reducible biomimetic block copolymers.

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1
Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamate-cho, Suita-shi, Osaka 564-8680, Japan. yasu.bmt@kansai-u.ac.jp.

Abstract

Biomimetic block copolymer-protected gold nanoparticles (AuNPs) were prepared by autoreduction. Excellent colloidal stability of the AuNPs was observed at a high salt concentration and over a wide pH range. Functional AuNPs are useful for label-free detection of an inflammation biomarker, C-reactive protein (CRP).

PMID:
24752806
DOI:
10.1039/c4cc01855a
[Indexed for MEDLINE]
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