Comparing clinical characteristics between hospitalized adults with laboratory-confirmed influenza A and B virus infection

Su Su; Sandra S Chaves; Alejandro Perez; Tiffany D'Mello; Pam D Kirley; Kimberly Yousey-Hindes; Monica M Farley; Meghan Harris; Ruta Sharangpani; Ruth Lynfield; Craig Morin; Emily B Hancock; Shelley Zansky; Gary E Hollick; Brian Fowler; Christie McDonald-Hamm; Ann Thomas; Vickie Horan; Mary Lou Lindegren; William Schaffner; Andrea Price; Ananda Bandyopadhyay; Alicia M Fry

doi:10.1093/cid/ciu269

Comparing clinical characteristics between hospitalized adults with laboratory-confirmed influenza A and B virus infection

Clin Infect Dis. 2014 Jul 15;59(2):252-5. doi: 10.1093/cid/ciu269. Epub 2014 Apr 18.

Authors

Su Su¹, Sandra S Chaves², Alejandro Perez², Tiffany D'Mello¹, Pam D Kirley³, Kimberly Yousey-Hindes⁴, Monica M Farley⁵, Meghan Harris⁶, Ruta Sharangpani⁷, Ruth Lynfield⁸, Craig Morin⁸, Emily B Hancock⁹, Shelley Zansky¹⁰, Gary E Hollick¹¹, Brian Fowler¹², Christie McDonald-Hamm¹³, Ann Thomas¹⁴, Vickie Horan¹⁵, Mary Lou Lindegren¹⁶, William Schaffner¹⁶, Andrea Price¹⁷, Ananda Bandyopadhyay¹⁸, Alicia M Fry²

Affiliations

¹ Influenza Division, Centers for Disease Control and Prevention Atlanta Research and Education Foundation, Atlanta, Georgia.
² Influenza Division, Centers for Disease Control and Prevention.
³ California Emerging Infections Program, Oakland.
⁴ Connecticut Emerging Infectious Program, Yale University, New Haven, Connecticut.
⁵ School of Medicine, Emory University, and Atlanta Veterans Affairs Medical Center, Atlanta, GA.
⁶ Iowa Department of Public Health, Des Moines.
⁷ Michigan Department of Community Health, Lansing.
⁸ Minnesota Department of Health, St. Paul.
⁹ New Mexico Department of Health, Santa Fe.
¹⁰ Emerging Infections Program, New York State Department of Health, Albany.
¹¹ Department of Medicine, University of Rochester School of Medicine and Dentistry, New York.
¹² Ohio Department of Health, Columbus.
¹³ Oklahoma State Department of Health, Oklahoma City.
¹⁴ Oregon Public Health Division, Portland.
¹⁵ South Dakota Department of Health, Pierre.
¹⁶ Vanderbilt University School of Medicine, Nashville, Tennessee.
¹⁷ Salt Lake County Health Department, Salt Lake City, Utah.
¹⁸ The Bill & Melinda Gates Foundation, Seattle, Washington.

PMID: 24748521
DOI: 10.1093/cid/ciu269

Abstract

We challenge the notion that influenza B is milder than influenza A by finding similar clinical characteristics between hospitalized adult influenza-cases. Among patients treated with oseltamivir, length of stay and mortality did not differ by type of virus infection.

Keywords: adult; antiviral treatment; hospitalization; influenza A and B virus infection.

Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Publication types

Comparative Study
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Antiviral Agents / therapeutic use
Female
Humans
Influenza A virus / isolation & purification*
Influenza B virus / isolation & purification*
Influenza, Human / mortality
Influenza, Human / pathology*
Influenza, Human / virology*
Length of Stay
Male
Middle Aged
Oseltamivir / therapeutic use
Survival Analysis
Young Adult

Substances

Antiviral Agents
Oseltamivir

Grants and funding

5U38HM000414/HM/NCHM CDC HHS/United States