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J Vis Exp. 2014 Apr 10;(86). doi: 10.3791/51449.

Determination of the spontaneous locomotor activity in Drosophila melanogaster.

Author information

1
Genetics and Developmental Biology, School of Medicine, University of Connecticut Health Center.
2
Genetics and Developmental Biology, School of Medicine, University of Connecticut Health Center; Rogina@neuron.uchc.edu.

Abstract

Drosophila melanogaster has been used as an excellent model organism to study environmental and genetic manipulations that affect behavior. One such behavior is spontaneous locomotor activity. Here we describe our protocol that utilizes Drosophila population monitors and a tracking system that allows continuous monitoring of the spontaneous locomotor activity of flies for several days at a time. This method is simple, reliable, and objective and can be used to examine the effects of aging, sex, changes in caloric content of food, addition of drugs, or genetic manipulations that mimic human diseases.

PMID:
24747955
PMCID:
PMC4166174
DOI:
10.3791/51449
[Indexed for MEDLINE]
Free PMC Article

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