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Worm. 2013 Oct 1;2(4):e26454. doi: 10.4161/worm.26454. Epub 2013 Sep 30.

Food, pathogen, signal: The multifaceted nature of a bacterial diet.

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1
Program in Systems Biology; Program in Molecular Medicine; University of Massachusetts Medical School; Worcester, MA USA.

Abstract

C. elegans, both in the wild and in the lab, live on a diet of live bacteria. The bacterial diet provides nutrients for C. elegans, but can also play a number of other roles in C. elegans physiology. Recently, we compared the effects of different bacterial diets on life history traits and gene expression. Here, we discuss our recent findings in the context of other dietary studies and highlight challenges in understanding dietary effects. For instance, since bacteria can be pathogenic it can be difficult to disentangle pathogenic from dietary effects. Here we summarize different bacterial diets used for C. elegans and how they affect the animal.

KEYWORDS:

C. elegans; Comamonas; E. coli; Pseudomonas; bacteria; diet; hormone; life history traits; nutrient; pathogen

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