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Obes Surg. 2014 Jun;24(6):971-3. doi: 10.1007/s11695-014-1246-6.

Correlation between post over preoperative surrogate insulin resistance indexes' ratios and reversal of metabolic syndrome after Roux-en-Y gastric bypass.

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Department of Surgery, Faculty of Medical Sciences, State University of Campinas (UNICAMP), R. Hermantino Coelho, 77/03-11, 13087-500, Campinas, Sao Paulo, Brazil,


Metabolic syndrome (MetS) is strongly linked to insulin resistance and has a high resolution rate after bariatric surgery. This study aims to determine whether post over preoperative ratios of surrogate insulin resistance markers (HOMA, TyG, and TG/HDL-c) are associated to postsurgical MetS reversal. This is a retrospective cohort study which involved 96 subjects with MetS who underwent Roux-en-Y gastric bypass (RYGB). Post over preoperative ratios of TyG and TG/HDL-c indexes were statistically associated to MetS resolution. The use of these ratios as a way to assess postsurgical insulin sensitivity response appears to be a simple and useful tool in clinical practice.

[Indexed for MEDLINE]

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