Friction on MAP determines its traveling direction on microtubules

Sadanori Watanabe; Gohta Goshima

doi:10.1016/j.devcel.2014.03.022

Friction on MAP determines its traveling direction on microtubules

Dev Cell. 2014 Apr 14;29(1):5-6. doi: 10.1016/j.devcel.2014.03.022.

Authors

Sadanori Watanabe¹, Gohta Goshima²

Affiliations

¹ Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
² Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan. Electronic address: goshima@bio.nagoya-u.ac.jp.

PMID: 24735876
DOI: 10.1016/j.devcel.2014.03.022

Abstract

Microtubule networks generate various forces, and the forces are applied to microtubule-associated proteins (MAPs). Forth et al. (2014) show in a recent issue of Cell that asymmetric frictional force between MAPs and microtubules leads to directional movement of MAPs along microtubules, providing insight into the mechanism of microtubule network self-organization.

Publication types

Comment

MeSH terms

Antigens, Nuclear / metabolism*
Cell Cycle Proteins / metabolism*
Microtubule-Associated Proteins / metabolism*
Microtubules / metabolism*
Nuclear Matrix-Associated Proteins / metabolism*

Substances

Antigens, Nuclear
Cell Cycle Proteins
Microtubule-Associated Proteins
Nuclear Matrix-Associated Proteins