Format

Send to

Choose Destination
See comment in PubMed Commons below
Mult Scler Int. 2014;2014:872732. doi: 10.1155/2014/872732. Epub 2014 Mar 5.

Fatigue is associated with poor sleep in people with multiple sclerosis and cognitive impairment.

Author information

1
Department of Neurology, School of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road L226, Portland, OR 97239, USA ; Multiple Sclerosis Center of Excellence-West, Portland Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.
2
Portland Lung Clinic, Adventist Medical Center, Portland, OR 97216, USA.
3
Department of Neurology, School of Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road L226, Portland, OR 97239, USA ; Department of Medical Informatics and Clinical Epidemiology, School of Medicine, Oregon Health & Science University, Portland, OR 97239, USA ; Epilepsy Center of Excellence, Portland Veterans Affairs Medical Center, Portland, OR 97239, USA.
4
Department of Neurology, School of Medicine, Louisiana State University Health Sciences Center-New Orleans, New Orleans, LA 70112, USA.
5
National Center for Rehabilitative Auditory Research, Portland Veterans Affairs Medical Center, Portland, OR 97239, USA.
6
Department of Rehabilitation Medicine, University of Washington, VA Puget Sound Health Care System, VA MS Center of Excellence-West, Seattle, WA 98108, USA.
7
Department of Rehabilitation Medicine, University of Washington, VA Puget Sound Health Care System, VA MS Center of Excellence-West, Seattle, WA 98108, USA ; Department of Epidemiology, University of Washington, VA Puget Sound Health Care System, VA MS Center of Excellence-West, Seattle, WA 98108, USA.

Abstract

Background. Fatigue is the most common symptom in people with multiple sclerosis (MS). Poor sleep also occurs in this population. Objective. The objective of this study was to determine the relationship between fatigue and sleep quality in people with MS and cognitive impairment. Method. This cross-sectional study assessed relationships among fatigue, assessed with the Modified Fatigue Impact Scale (MFIS) and the Fatigue Severity Scale (FSS), sleep quality assessed with the Pittsburg Sleep Quality Index (PSQI), and demographics in 121 people with MS and cognitive impairment. Results. Fatigue was significantly correlated with poor sleep quality (MFIS: F = 15.60, P < 0.01; FSS: F = 12.09, P < 0.01). FSS scores were also significantly correlated with the PSQI subscore for daytime dysfunction and MFIS scores were significantly correlated with disability, age, and the PSQI subscores for sleep quality, sleep duration, and daytime dysfunction. Conclusions. This study demonstrates a relationship between fatigue and sleep quality in individuals with MS and cognitive impairment.

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Support Center