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Front Neuroinform. 2014 Mar 27;8:30. doi: 10.3389/fninf.2014.00030. eCollection 2014.

The multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) high performance computing infrastructure: applications in neuroscience and neuroinformatics research.

Author information

1
Monash eResearch Centre, Monash University Clayton, VIC, Australia.
2
Australian Synchrotron Clayton, VIC, Australia.
3
CSIRO Clayton, VIC, Australia.
4
Centre for Advanced Imaging, University of Queensland St Lucia, QLD, Australia.
5
The University of Melbourne Melbourne, VIC, Australia.
6
Monash Biomedical Imaging, Monash University Clayton, VIC, Australia ; CSIRO Preventative Health Flagship, CSIRO Computational Informatics, The Australian e-Health Research Centre Herston, QLD, Australia.
7
Monash eResearch Centre, Monash University Clayton, VIC, Australia ; Monash Biomedical Imaging, Monash University Clayton, VIC, Australia.
8
Monash eResearch Centre, Monash University Clayton, VIC, Australia ; Monash Biomedical Imaging, Monash University Clayton, VIC, Australia ; Life Sciences Computation Centre, VLSCI Parkville, VIC, Australia.
9
Monash Biomedical Imaging, Monash University Clayton, VIC, Australia.

Abstract

The Multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) is a national imaging and visualization facility established by Monash University, the Australian Synchrotron, the Commonwealth Scientific Industrial Research Organization (CSIRO), and the Victorian Partnership for Advanced Computing (VPAC), with funding from the National Computational Infrastructure and the Victorian Government. The MASSIVE facility provides hardware, software, and expertise to drive research in the biomedical sciences, particularly advanced brain imaging research using synchrotron x-ray and infrared imaging, functional and structural magnetic resonance imaging (MRI), x-ray computer tomography (CT), electron microscopy and optical microscopy. The development of MASSIVE has been based on best practice in system integration methodologies, frameworks, and architectures. The facility has: (i) integrated multiple different neuroimaging analysis software components, (ii) enabled cross-platform and cross-modality integration of neuroinformatics tools, and (iii) brought together neuroimaging databases and analysis workflows. MASSIVE is now operational as a nationally distributed and integrated facility for neuroinfomatics and brain imaging research.

KEYWORDS:

CT reconstruction; Huntington's disease; Quantitative susceptibility mapping; cloud computing; digital atlasing; high performance computing; instrument integration; neuroinformatics infrastructure

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