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Zhonghua Yi Xue Za Zhi. 2014 Jan 14;94(2):96-9.

[Diagnosis and treatment of solid-pseudopapillary carcinoma of the pancreas].

[Article in Chinese]

Author information

1
Department of Abdominal Surgery, Cancer Institute & Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
2
Department of Abdominal Surgery, Cancer Institute & Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China. Email: wangcf369@medmail.com.cn.

Abstract

OBJECTIVE:

To summarize the institutional experiences of diagnosis, treatment and prognosis for solid-pseudopapillary carcinoma of the pancreas (SPCP).

METHODS:

Retrospective analyses were performed for 11 cases of SPCP diagnosed in recent 15 years at Department of Abdominal Surgery, Cancer Institute and Hospital, Chinese Academy of Medical Sciences.

RESULTS:

There were 10 females and 1 male with an average age of 33 years. The locations included head (n = 7) and body and tail (n = 4).Five of them had pain in abdomen or back while another 6 were found accidentally. Their images were of solid-cystic tumors and all serum markers stayed within a normal range. All received en bloc resection. The average maximum diameter was 6 cm and the percentage of patients with lymph node metastases was 36.4% (4/11). Their average follow-up period was 80.5 months. Two patients died postoperatively from hepatic metastases. And another 9 survived without relapse or metastasis.

CONCLUSION:

As one of rare pancreatic neoplasms with non-specific clinical characteristics, SPCP primarily affects young females. A definite diagnosis depends on pathological confirmation.Surgery is the first-choice treatment with a favorable prognosis.Radical resection with R0 margin is crucial to long-term postoperative survival.

PMID:
24721347
[Indexed for MEDLINE]
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