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Virol J. 2014 Apr 9;11:68. doi: 10.1186/1743-422X-11-68.

Prospective study of Hepatitis E Virus infection among pregnant women in France.

Author information

1
AP-HP, Hôpital Paul Brousse, Virologie, Villejuif 94804, France. anne-marie.roque@pbr.aphp.fr.

Abstract

BACKGROUND:

Hepatitis E Virus (HEV) infection has a poor prognosis among pregnant women from high endemic countries. HEV-prevalence and incidence among pregnant women is unknown in high-income countries such as France. This prospective study was conducted to assess HEV infection in this setting.

FINDINGS:

An overall HEV prevalence of 7.74% was observed among 315 pregnant women. Seroprevalence was higher in south than in north of France (29.3% vs. 3.6%, p < 0.0001), and women with detectable IgG were older. No IgG seroconversion or IgM detection were observed during pregnancy.

CONCLUSIONS:

Data suggest that HEV infection is a rare occurrence during pregnancy even in regions of western countries with high seroprevalence rates.

PMID:
24716485
PMCID:
PMC4011159
DOI:
10.1186/1743-422X-11-68
[Indexed for MEDLINE]
Free PMC Article
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