Development of multi-functional chelators based on sarcophagine cages

Molecules. 2014 Apr 3;19(4):4246-55. doi: 10.3390/molecules19044246.

Abstract

A new class of multifunctionalized sarcophagine derivatives was synthesized for 64Cu chelation. The platform developed in this study could have broad applications in 64Cu-radiopharmaceuticals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chelating Agents / chemical synthesis*
  • Chelating Agents / chemistry
  • Coordination Complexes / chemical synthesis*
  • Coordination Complexes / chemistry
  • Copper Radioisotopes / chemistry
  • Dipeptides / chemistry*
  • Isotope Labeling / methods
  • Positron-Emission Tomography
  • Radiopharmaceuticals / chemistry

Substances

  • Chelating Agents
  • Coordination Complexes
  • Copper Radioisotopes
  • Dipeptides
  • Radiopharmaceuticals
  • alanyltyrosine