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Ann Vasc Surg. 2014 Aug;28(6):1479-84. doi: 10.1016/j.avsg.2014.03.024. Epub 2014 Apr 2.

Indocyanine green angiography for the diagnosis of peripheral arterial disease with isolated infrapopliteal lesions.

Author information

1
Division of Vascular and Endovascular Surgery, Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: igari.srg1@tmd.ac.jp.
2
Division of Vascular and Endovascular Surgery, Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

Abstract

BACKGROUND:

In this study, we evaluated the accuracy of the indocyanine green angiography (ICGA) test to diagnose peripheral arterial disease (PAD) with isolated infrapopliteal lesions.

METHODS:

This study was undertaken from a retrospective review of PAD patients with isolated infrapopliteal lesions who underwent ICGA between November 2012 and July 2013. We calculated the ICGA parameters while comparing the findings with the ankle-brachial index (ABI) and toe-brachial index (TBI) in patients with infrapopliteal lesions.

RESULTS:

Twenty-three limbs with isolated infrapopliteal lesions in 14 PAD patients and 15 limbs without arterial lesions in 9 control patients were examined using ABI, TBI, and ICGA. The Td 90% (the time elapsed from the maximum intensity to 90% of the maximum intensity) correlated most significantly with the ABI value. A cutoff value of Td 90% >25 sec also significantly correlated with the presence of PAD (sensitivity, 82.6%).

CONCLUSIONS:

ICGA might therefore be useful for assessing the peripheral perfusion quantitatively, even in PAD patients with isolated infrapopliteal lesions. The use of Td 90% on ICGA may also be effective for accurately estimating the presence of PAD.

PMID:
24704053
DOI:
10.1016/j.avsg.2014.03.024
[Indexed for MEDLINE]
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