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J Oral Maxillofac Surg. 2014 Aug;72(8):1504-10. doi: 10.1016/j.joms.2014.02.025. Epub 2014 Feb 21.

Transarterial embolization of mandibular arteriovenous malformations using ONYX.

Author information

1
Attending Physician, Interventional Neuroradiology Unit, Department of Diagnostic Imaging, Monash Medical Center, Monash Health, Melbourne, Victoria, Australia.
2
Instructor of Neurology, Neurointerventional Service and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
3
Associate Professor of Radiology, Division Chief Interventional and Neurointerventional Radiology, Neurointerventional Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA.
4
Professor of Oral and Maxillofacial Surgery, Department Head OMFS, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
5
Associate Professor of Radiology, Neurointerventional Service and Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA. Electronic address: jrabinov@partners.org.

Abstract

PURPOSE:

To document the efficacy of ethylene vinyl alcohol copolymer (ONYX; ev3/Covidien, Irvine, CA) in the treatment of arteriovenous malformations (AVMs) of the mandible.

MATERIALS AND METHODS:

A retrospective consecutive series of patients with facial AVMs isolated to the mandible and immediate perimandibular tissue was identified at 2 institutions. The primary treatment modality of transarterial embolization using ONYX was performed by way of the external carotid artery branches. Staged procedures were accomplished until no arteriovenous shunt remained. A 1-year follow-up angiogram was obtained for each patient.

RESULTS:

Three patients, aged 8 (patient 1), 16 (patient 2), and 17 (patient 3) years presented with bleeding from facial AVMs isolated to the mandible. Patient 1 was female and patients 2 and 3 were male. The 2 older patients had loose molar or canine dentition. Transarterial embolization with ONYX achieved complete angiographic closure of the arteriovenous shunt in each patient. A total of 1, 6, and 3 staged embolization procedures were performed in the 3 patients. Patient 2 had mild transient facial numbness after embolization that completely resolved. Patient 3 had loose molars associated with the AVM that were extracted for treatment of intraprocedural bleeding. The 1-year angiographic follow-up data demonstrated durable closure of all 3 lesions.

CONCLUSIONS:

Transarterial embolization of high-flow intraosseus mandibular AVMs was safely accomplished with ONYX in our small retrospective cohort. Complete, durable occlusion was found on the angiogram at 1 year, with clinical stability extending to an average of 3 years. Surgical resection of the AVM was avoided in all 3 patients.

PMID:
24704035
DOI:
10.1016/j.joms.2014.02.025
[Indexed for MEDLINE]
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