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J Aging Health. 2014 Jun;26(4):583-599. Epub 2014 Apr 2.

Association Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease.

Author information

1
Reading Health System, West Reading, PA, USA a.yazzzd@gmail.com.
2
Atlantic Health System, Morristown, NJ, USA.
3
University of Arizona, Tuscon, USA.
4
Temple University, Philadelphia, PA, USA.
5
University of Pittsburgh, PA, USA.

Abstract

OBJECTIVE:

To examine the association between 6-min walk test (6 MWT) performance and all-cause mortality, coronary heart disease mortality, and incident coronary heart disease in older adults.

METHOD:

We conducted a time-to-event analysis of 1,665 Cardiovascular Health Study participants without prevalent cardiovascular disease with a 6 MWT.

RESULTS:

During a mean follow-up of 8 years, there were 305 incident coronary heart disease events, and 504 deaths of which 100 were coronary heart disease-related deaths. The 6 MWT performance in the shortest two distance quintiles was associated with increased risk of all-cause mortality (290-338 m: hazard ratio [HR] = 1.7; 95% confidence interval [CI] = [1.2, 2.5]; <290 m: HR = 2.1; 95% CI = [1.4, 3.0]). The adjusted risk of coronary heart disease mortality incident events among those with a 6 MWT < 290 m was not significant.

DISCUSSION:

Performance on the 6 MWT is independently associated with all-cause mortality and is of prognostic utility in community-dwelling older adults.

KEYWORDS:

exercise; geriatrics; mortality; physical function

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