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Scand J Gastroenterol. 2014 Jun;49(6):722-6. doi: 10.3109/00365521.2014.899619. Epub 2014 Apr 2.

MRI-guided percutaneous transhepatic cholangiodrainage: feasibility study in a porcine model.

Author information

1
Department of Internal Medicine, Division of Hepatology & Gastroenterology, Charité Campus Virchow Clinic , Augustenburger Platz 1, D-13353, Berlin , Germany.

Abstract

BACKGROUND AND STUDY AIMS:

MRI-guided procedures combine high-quality imaging with lack of radiation. Percutaneous transhepatic cholangiodrainage under real-time MRI guidance (MRI-PTCD) seems promising, allowing targeted puncture and avoiding multiple blind passes and use of contrast, which are associated with standard PTCD's heaviest complications.

PATIENTS AND METHODS:

Aim of this study was to investigate the feasibility of MRI-PTCD in three outbred piglets. Obstructive cholestasis was induced by common bile duct ligation. Two days later, MRI-PTCD was performed (open MRI, 1.0 Tesla) with prototype MRI-compatible accessories. Visualization was achieved with a balanced steady-state free precession real-time sequence (bSSFP: 0.75 frames/s, TR/TE [ms]: 7.2/3.6; flip angle: 45°; 200 × 200 matrix size; resolution: 1.3 × 1.3 mm(2), slice thickness: 7 mm). Cannulation of the bile ducts was followed by placement of Yamakawa drainages.

RESULTS:

Twelve punctures were performed (four per animal, 10/12 successful); in 2/10 the bile ducts could not be cannulated. Animal survival was 100% and no significant complications occurred.

CONCLUSIONS:

Initial data show that MRI-PTCD can be successfully performed. This may lead to establishment of a new optimized PTCD technique compared to the standard approach under fluoroscopy.

KEYWORDS:

MRI guidance; MRI-PTCD; PTCD; real-time open MRI

PMID:
24694300
DOI:
10.3109/00365521.2014.899619
[Indexed for MEDLINE]

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