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Arch Gynecol Obstet. 2014 Aug;290(2):389-93. doi: 10.1007/s00404-014-3218-4. Epub 2014 Apr 2.

Vulvodynia and proctodynia treated with topical baclofen 5 % and palmitoylethanolamide.

Author information

1
Institute for Neuropathic Pain, Spoorlaan 37a, 3735 MV, Bosch en Duin, The Netherlands, jan@neuropathie.nu.

Abstract

BACKGROUND:

The prevalence of idiopathic vulvodynia and proctodynia is high. Pain management with anti-depressants and anti-epileptics may induce undesirable side effects. Therefore, topical baclofen cream and palmitoylethanolamide might be new therapeutic options.

CASE:

A 33-year-old woman with intractable chronic vulvar and anal pain had to abstain from sexual intercourse and could neither cycle nor sit for more than 5 min. The patient did not respond to standard treatments. We prescribed a combination of topical baclofen 5 % and palmitoylethanolamide 400 mg, three times daily. After 3 months her symptoms decreased more than 50 % and sexual intercourse was possible again without pain.

CONCLUSION:

Topical baclofen and palmitoylethanolamide can be a viable treatment option in chronic vulvodynia and proctodynia.

PMID:
24691823
DOI:
10.1007/s00404-014-3218-4
[Indexed for MEDLINE]

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