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Clin Rehabil. 2014 Sep;28(9):902-11. doi: 10.1177/0269215514527299. Epub 2014 Apr 1.

Randomized cross-over trial to investigate the efficacy of a two-week physiotherapy programme with repetitive exercises of cueing to reduce the severity of freezing of gait in patients with Parkinson's disease.

Author information

1
Schön Klinik München Schwabing, Munich, Germany.
2
Schön Klinik München Schwabing, Munich, Germany ACeballos-Baumann@schoen-kliniken.de.

Abstract

OBJECTIVE:

To investigate the efficacy of a two-week programme of repetitive exercise with cueing and movement strategies upon freezing of gait in people with Parkinson's disease.

DESIGN:

Randomized cross-over trial.

SETTING:

Specialist clinic for Parkinson's disease.

SUBJECTS:

A total of 22 patients with Parkinson's disease and freezing while other symptoms had favorably responded to dopaminergic treatment.

INTERVENTION:

Patients were randomized into a four-week cross-over trial, and received either treatment (Group 1) or no treatment (Group 2) during Period 1, and switched during Period 2. Treatment consisted of a two-week programme during which the patients exercised cueing, and movement strategies together with a physiotherapist.

MAIN MEASURE:

The primary outcome measure was a freezing score assessed from blinded and random ratings of video recordings. The secondary outcome measure was a patient-reported freezing questionnaire. Mean differences between the treatment periods (treatment arms) were evaluated for treatment (period) effects. Sums of treatment periods were evaluated for carry-over effects.

RESULTS:

The programme led to a significant treatment effect in the freezing score of 3.0 improvement (95% confidence interval 0.9-5.0; p < 0.01). No carry-over or period effects were detected. The questionnaire revealed a period effect, so groups were compared after Period 1, where a significant difference was found (15.0 vs. 11.7; p < 0.05).

CONCLUSIONS:

The two-week physiotherapy programme reduced the severity of freezing in patients with Parkinson's disease.

KEYWORDS:

Parkinson’s disease; Randomized cross-over trial; freezing; gait; physiotherapy

PMID:
24691217
DOI:
10.1177/0269215514527299
[Indexed for MEDLINE]
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