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Bull Cancer. 2014 Mar;101(3):243-9. doi: 10.1684/bdc.2014.1903.

[Home parenteral nutrition in elderly patients with cancer: an observational prospective study].

[Article in French]

Author information

Polyclinique privée, Service d'oncologie, 1, rue Robert-Debré, 41260 La Chaussée-Saint-Victor, France.
Département scientifique, ClinSearch, 1, avenue de l'Égalité, 92220 Bagneux, France.
Département de gastroentérologie et nutrition clinique, Val d'Aurelle, 208, avenue des Apothicaires, 34298 Montpellier cedex 5, France.
Centre Frédéric-Joliot, 7, rue de l'Abreuvoir, 76000 Rouen, France.
Centre d'oncologie et radiothérapie, 14, allées Paulmy, 64100 Bayonne, France.
Hôpital Antoine-Béclère, Service d'hépatogastroentérologie, 157, rue de la Porte-de-Trivaux, 92140 Clamart, France.
Hôpital Henri-Mondor, Service d'oncologie, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
CLCC, 3, rue de la porte-de-l'Hôpital, 67000 Strasbourg, France.
Hospices Civils de Lyon, Service de nutrition clinique intensive, 103, Grande-Rue de la Croix-Rousse, 69317 Lyon cedex 04, France.


Malnutrition is a bad prognostic factor that reduces the quality of life (QoL) in patients with cancer. The objective was to assess the impact of home parenteral nutrition (HPN) on the QoL of elderly malnourished patients with cancer. This French prospective observational study included patients, aged 70 years or older, with cancer, for whom HPN was prescribed for at least 14 days. The patient, the physician and a family member or home caregiver had to fill in a questionnaire at inclusion and 28 days later. Included patients (n = 221) were mainly suffering from a digestive cancer. After HPN intake, improved weight was noticed in 68% and 14% of patients had reached the target weight. Improved global QoL was reported in 59% of patients. Physicians noticed a significant improvement for the same compounds. These results suggest a benefit of the HPN on the nutritional status and QoL in elderly patients with cancer. Further controlled randomised trials are needed to prove the benefit of HPN in the routine management of these patients.


cancer; elderly patients; home parenteral nutrition; nutritional status; quality of life

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